Prostate Support Softgels

Indications

Prostate Support Softgels has the following benefits:

• Promotes healthy circulation
• Provides antioxidant protection
• Promotes healthy prostate function

Prostate Health Background & Application

As a normal part of aging, the prostate gland swells in size and may result in signs and symptoms of Benign Prostatic Hypertrophy (BPH). Certain nutrients influence the growth and blood flow to the prostate.

Research Summaries

Pumpkin Seed Oil

Pumpkin seeds contain large amounts of long chain fatty acids and phytochemicals that have been shown to aid in prostate health. The German Commission E has approved Pumpkin Seed Oil for problems of Stage 1 or 2 levels of BPH. It also shows anti-androgenic and anti-inflammatory effects. Subjects in one study showed a decline in dihydrotestosterone levels in prostatic tissue when using pumpkin seed and saw palmetto¹. Another study showed a reduction in symptoms in patients with BPH given pumpkin seed oil².

Saw Palmetto, Nettle & Pygeum

Saw Palmetto has been extensively researched for its role in BPH and prostate cancer. A recent study published in Endocrinology showed Saw Palmetto inhibited IGF-1 signaling pathway thereby mediating antiproliferative effects on prostate cells³. Nettle, too, exhibits an antiproliferative effect in human prostate cancer development⁴. Pygeum has also shown this effect⁵ in both BPH and prostate cancer cells.

Lycopene

Lycopene may exert chemoprotective effects through hormone modulation, carcinogen metabolism, and immune system function. Research links it to reductions in skin, breast, prostate, digestive tract, cervix and bladder cancer risk. Research has shown that lycopene supplementation with 15 mg of the substance reduced the growth of prostate cancer in men newly diagnosed with the disease⁶. Additional research demonstrates that lycopene appears to interfere with IGF-I receptor signaling and cell cycle progression in mammary cancer cells⁷.

Selenium

A 2005 study in Neoplasma showed that low serum selenium concentrations were observed in both BPH and prostate cancer patients compared with healthy controls⁸.

Our Product

Our product contains 1200 mg Pumpkin Seed Oil, 300 mg Saw Palmetto, 150 mg Nettle, 100 mg Pygeum, 100 mg phytosterols (including beta-sitosterol), 100 mg green tea extract, 50 mg soy isoflavones, 30 mg Lycopene, and 30 IU vitamin E, 15 mg zinc, and 70 mcg selenium.

Dosage

Take one softgel twice daily.

Specifications

Product Name:       Prostate Support Softgels

Label Claim:           Supports Prostate Health

How Supplied:        Softgel capsule

Product Code:         VL154

References

1. The Physician’s Desk Reference for Herbal Medicines, 2004. Medical Economics Company, Inc. Montvale, NJ.
2. Carbin, B.E., B. Larsson, O. Lindahl. 1990. Treatment of benign prostatic hyperplasia with phytosterols. Br J Urol 66(6):639–641.
3. Wadsworth TL, et al. Saw Palmetto Extract Suppresses Insulin-Like Growth Factor-I Signaling and Induces Stress-Activated Protein Kinase/c-Jun N-Terminal Kinase Phosphorylation in Human Prostate Epithelial Cells. 2004, Endocrinology Vol. 145, No. 7 3205-3214
4. Konrad L, et al. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta Med. 2000 Feb;66(1):44-7.
5. Santa Maria Margalef A, et al. Antimitogenic effect of Pygeum africanum extracts on human prostatic cancer cell lines and explants from benign prostatic hyperplasia. Arch Esp Urol. 2003 May;56(4):369-78.
6. Omer K, et al. Phase II randomized Clinical Trial of Lycopene Supplementation before Radical Prostatectomy. Cancer Epidemiology, Biomarkers & Prevention, Vol.10,861-868, August 2001.
7. Karas M. Lycopene interferes with cell cycle progression and insulin-like growth factor I signaling in mammary cancer cells. Nutr Cancer, 2000;36(1):101-111.
8. Zachara BA, et al. Blood and tissue selenium concentrations and glutathione peroxidase activities in patients with prostate cancer and benign prostate hyperplasia. Neoplasma. 2005;52(3):248-54.