Brain Support Softgels

Indications

Brain Support Softgels has the following benefits:

• Promotes healthy circulation
• Provides antioxidant protection
• May keep homocysteine levels in check

Brain Health Background & Application

A healthy brain is maintained in part by a healthy diet. Mental stimulation, exercise and injury prevention also weigh in. All of these elements support healthy circulation to the brain in order for it to function well. Certain nutrients that may be lacking in the typical American diet influence blood flow to the brain and beyond. Research shows the important role some nutrients play in improving memory and cognition.

Research Summaries

Fish Oils

It is well established that DHA is taken up by brain cells, especially important for prenatal and postnatal brain development. One study showed that intake of DHA and phosphatidylcholine improved maze-learning ability and brain function in both old and young mice¹. Another showed that DHA acts as a precursor to “neuroprotective signaling responses to ischemia-repurfusion, suggesting therapeutic use for stroke, neurotrauma, spinal cord injury, and neurodegenerative diseases².”

Phosphatides

Multiple clinical trials have been done using the trademarked SerinAid™ complex. Results from these show improvements in cognitive measures such as memory, mood, and behavior in both elderly and/or Alzheimer’s patients. In a majority of the trials, patients were given a placebo or 300mg of SerinAid™ daily for a range of 60-180 days³.

Vitamins B6, B12, Folate

B-vitamins play multiple roles in brain health. Deficiencies of these result in neurological pathologies, in part due to subsequent elevation of homocysteine levels⁴. Elevated homocysteine levels in the brain are neurotoxic and have negative vascular effects⁵. A number of studies show relationships between these B-vitamins and the prevention of or treatment of dementia, including Alzheimer’s disease (AD). A recent study showed folate deficiency alone may “precede AD and vascular dementia onset,⁶” with another supporting that folate and B12 are clearly associated with the development of AD⁷.

Ginkgo Biloba

The Journal of the American Medical Association published results of a 52-week study utilizing ginkgo showing improvements in mental performance in about 1/3 of AD patients studied⁸. Another showed that supplementation with 80 mg of ginkgo three times daily for three months showed improvements in memory, attention, and psychomotor performance in AD patients compared to placebo after one month⁹.

Our Product

Our product contains 300 mg EPA, 200 mg DHA, 120 mg Ginkgo biloba, 100 mg SerinAid™ phosphatidylserine complex, phosphatidylcholine, inositol, rosemary, vitamins B6, B12 and folate, and vitamin E.

Dosage

Take one softgel twice daily.

Specifications

Product Name:       Brain Support Softgels

Label Claim:           Supports Brain Health

How Supplied:        Softgel capsule

Product Code:         VL153

References

1. Lim SY, et al. Intakes of dietary docosahexaenoic acid ethyl ester and egg phosphatidylcholine improve maze-learning ability in young and old mice. 2000;130:1629-1632. Journal of Nutrition.
2. Bazan NG. Neuroprotectin D1 (NPD1):a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress. Apr 2005;15(2):159-66. Brain Pathology
3. For all SerinAid™ abstracts, see: www.cheminutra.com/research.html
4. The Physician’s Desk Reference for Nutritional Supplements, 2001. Medical Economics Company, Inc. Montvale, NJ.
5. Garcia A, et al. Homocysteine and cognitive function in elderly people. Oct 2004;171(8) Can Med Assoc Jour
6. Quandri P, et al. Homocysteine, folate, and vitamin B12 in mild cognitive impairment, Alzheimer disease and vascular dementia. 2004;80:114-22 Amer Jour Clin Nutr
7. Wang BA, et al. Vitamin B12 and folate in relation to the development of AD. 2001;56:1188-1194 Neurology
8. LeBar PL, et al. A placebo-controlled, double-blind, randomized trial of an extract of ginkgo biloba for dementia. 1997;278(16):1327-1333 Jour Amer Med Assoc.
9. Hofferberth B. The efficacy of Egb761 in patients with senile dementia of the AD type, a double-blind, placebo-controlled study n different levels of investigation.1994;9:215-22. Human Psychopharmacology Clinical and Experimental.