Quercetin Complex

Indications

Quercetin has the following benefits:

• Antioxidant support.
• Promotes liver health.
• Supports healthy respiration and cardiovascular health.
• Weight loss / decreased adipose tissue
• Immune system support.
• Improved insulin sensitivity and glucose levels
• Obesity related inflammation and concerns

Introduction

Quercetin is a naturally occurring bioflavonoid, one of the most potent and widely dispersed throughout the plant kingdom. It has been intensely investigated for its numerous health benefits, primarily for its anti-inflammatory, anti-obesity and antioxidant properties.

Common Uses for Quercetin

Immune System – Historically this has been the focus for quercetin supplementation. Its role in capillary health and the respiratory system has made quercetin a popular product during seasonal changes. Also the diverse research for oxidative stress and inflammatory signal regulation has supported this demand.

Pancreatic and Liver Health – Quercetin has been shown to induce insulin secretion ^{(1, 2)} and decrease fat deposition in the liver ⁽³⁾. The potentiating effect of quercetin on glucose efficiency are results that quercetin, on its own, is capable of stimulating insulin secretion. This is accomplished by quercetin causing direct activation of the “long” calcium channels, which stimulates pancreatic beta cells to release insulin. Quercetin is being studied for its potential use in controlling obesity-related metabolic concerns.

Anti-obesity –Quercetin has been shown to modulate obesity-induced inflammation ^{(4, 5)} through protein kinase and signaling pathways. Recent research into obesity related metabolic disorders have shown quercetin to be a promising natural recommendation⁽⁶⁾. The hypoglycemic effects of quercetin has been reported in numerous animal studies, it may exert significant benefits in diabetic animals by limiting intestinal starch digestion, the production of glucose in the liver, increasing the uptake of glucose in skeletal muscle, and protecting against pancreatic islet damage.

Our Product

Our Quercetin Complex contains 250 mg of quercetin per vegetarian capsule. This is supported with the additional antioxidant protection of 100 mg of vitamin C and 50 mg of lemon bioflavonoids for a broader spectrum of coverage. Bromelain is added for proteolytic and absorption action. Magnesium is in this complex for its role in nearly all metabolic processes in the body, and for capillary health as endothelial cell migration requires magnesium.

Specifications

Product Name:       Quercetin Complex

Label Claim:     Supports the Body’s Response to Inflammation

How Supplied:     Vegetarian Capsule

Product Code:    VL181

References

1. Pon V, Dongmin L et al. Recent advances in understanding the anti-diabetic actions of dietary flavonoids. J Nutr Biochem. 2013 November; 24(11):

2. G Bardy, A Virsolvy, et al. Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells. BJP 2013; 169 1102-1113.

3. Kobori M et al. Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice. Mol. Nutr. Foods. Res. 2011 Apr; 66(4) 530-40.

4. Noh HJ1, Kim CS et al. Quercetin suppresses MIP-1α-induced adipose inflammation by downregulating its receptors CCR1/CCR5 and inhibiting inflammatory signaling. J Med Food. 2014 May; 17(5):550-7.

5. Ahn J, Lee H et al. The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways Biochem Biophys Res Commun. 2008 Sep 5; 373(4):545-9.

6. NH Le, C Kim et al. Quercetin Protects against Obesity-Induced Skeletal Muscle Inflammation and Atrophy. Med Inflammation 2014 Dec, Research Article ID 834294 Hindawi Pub.